Multimodal Evoked Potentials and Magnetic Resonance Imaging in Wilson's disease

Abstract

This study is about 7 patients with Wilson's disease, who were studied with multimodal evoked potentials and magnetic resonance imaging . Visual and somatosensory evoked potentials were normal in all patients, whereas brain stem auditory evoked potential abnormalities were detected in 5 of them. Magnetic resonance imaging studies of these 5 patients revealed widespread signal changes not only in basal ganglia but in thalamus, caudal midbrain and pons, though one of them was neurologically asymptomatic. Brain stem auditory evoked potentials were found to be correlated with magnetic resonance imaging results, however such a correlation was not present with the clinical status.