Clinical Spectrum of Bilateral Striatopallidodentate Calcinosis
Haşmet A. HANAĞASI, Figen HANAĞASI, Başar BİLGİÇ, Hakan GÜRVİT, Jale YAZICI, Murat EMRE
İstanbul Üniversitesi İstanbul Tıp Fakültesi Nöroloji Anabilim Dalı, İSTANBUL
Keywords: bilateral striopalidodentate calcinosis, parkinsonism, dementia, chorea, spasticity, treatment.
Abstract
Background: Bilateral striopalidodentate calcinosis (BSPDC) is a rare disorder where bilateral, symmetric, calcium and other mineral deposits occur in basal ganglia, thalamus, cerebellum, and white matter of the cerebral hemisphere. Neurological findings vary but movement disorders are the most common. Objectives: We report the clinical, neuroimaging and therapy results of 5 patients with BSPDC and review cases from literature. Discussion: Neurological disorders associated with BSPDC may show varied response to therapy.