Füsün Erdoğan1, Ferhan Soyuer2, Vesile Şenol2, Fehim Erman1

1Department Of Neurology, Erciyes University, Faculty Of Medicine, Kayseri, Turkey
2Halil Bayraktar Health Care School, Kayseri, Turkey

Keywords: epilepsy, event-related P300 potential, quality of life


OBJECTIVE: The assessment and understanding of the

impact of epiliepsy on an individual’s quality of life is increasingly being

recognized as an important component of clinical care. Cognitive and

behavioral deficits are more common in patients with epilepsy than in

the general population. Consequently, it is important to understanding

the relationship between quality of life and cognitive functions in the

clinical evaluation of epileptic patients.

Objectives: We aimed to evaluate the relationship between quality of

life and cognitive functions of our epileptic patients.

METHODS: Sixty-three epilepsy patients were evaluated.

They were over 18 years of age, seizure free with antiepileptic

medication and had mini mental state examination scores >24. Quality

of life was assessed with QOLIE-89 and cognitive functions were

evaluated with P300. The relationship between QOLIE-89 score, and

latancies and amplitude of P300 were analyzed.

RESULTS: No correlation was found between QOLIE-89 scores and P300


CONCLUSION: We did not find any correlation between quality of life

and P300 in epileptic patients whose seizures were under control with medication, which means that the cognitive conditions of these

patients do not effect their quality of life. The relationship between

quality of life and cognitive functions must be studied in more specific

epilepsy patient groups according to type of seizures, resistance to

medication, and effects of monothrapy and polytherapy. These kinds of

studies may lead to a greater contribution to the management of

epileptic patients.