Evaluation of Relationship Between Quality of Life and Event Related Potentials in Epileptic Patients
Füsün Erdoğan1, Ferhan Soyuer2, Vesile Şenol2, Fehim Erman1
1Department Of Neurology, Erciyes University, Faculty Of Medicine, Kayseri, Turkey
2Halil Bayraktar Health Care School, Kayseri, Turkey
Keywords: epilepsy, event-related P300 potential, quality of life
Abstract
OBJECTIVE: The assessment and understanding of the
impact of epiliepsy on an individual’s quality of life is increasingly being
recognized as an important component of clinical care. Cognitive and
behavioral deficits are more common in patients with epilepsy than in
the general population. Consequently, it is important to understanding
the relationship between quality of life and cognitive functions in the
clinical evaluation of epileptic patients.
Objectives: We aimed to evaluate the relationship between quality of
life and cognitive functions of our epileptic patients.
METHODS: Sixty-three epilepsy patients were evaluated.
They were over 18 years of age, seizure free with antiepileptic
medication and had mini mental state examination scores >24. Quality
of life was assessed with QOLIE-89 and cognitive functions were
evaluated with P300. The relationship between QOLIE-89 score, and
latancies and amplitude of P300 were analyzed.
RESULTS: No correlation was found between QOLIE-89 scores and P300
values.
CONCLUSION: We did not find any correlation between quality of life
and P300 in epileptic patients whose seizures were under control with medication, which means that the cognitive conditions of these
patients do not effect their quality of life. The relationship between
quality of life and cognitive functions must be studied in more specific
epilepsy patient groups according to type of seizures, resistance to
medication, and effects of monothrapy and polytherapy. These kinds of
studies may lead to a greater contribution to the management of
epileptic patients.