Clinic, Etiology and Prognosis in Cerebral Venous Thrombosis

Abstract

OBJECTIVE: Scientific BACKGROUND: Cerebral venous thrombosis is seen rarely according to arterial stroke and effects every age group. Onset and process is variable and usually a good prognosis occurs. Early development of coma and intracranial hemorrhage are bad prognostic factors. In our study, it is aimed to investigate the neurologic deficits, etiological factors, localization and the prognosis of the patients who are hospitalized with the diagnosis of cerebral venous thrombosis in our in-patient clinic.

METHODS: METHOD: Patients were investigated with routine hematologic, biochemical and vasculitic tests and cranial MRI and MR venography

RESULTS: RESULTS: Of fifteen patients, 10 were women and 5 were men. Mean age was 47.2 and age interval was 17-80. 5 patients in acute, 6 patients in subacute and 4 patients in chronic stage had admitted to our clinic. Mostly seen complaint was headache (11 patients) and 7 patients had paresis, 6 had epileptic seizures, 6 had visual deficits and 1 had unsteadiness. 9 patients had superior sagittal, 2 had superior sagittal+trasverse, 2 had superior sagittal+rectus+transverse, 1 had rectus+transverse and 1 had transverse sinus thrombosis. 2 patients had subarachnoid hemorrhage, 2 had lobar hematoma, 1 had subdural hematoma and 1 had hemorrhagic infarct. Etiologically 3 cases were in postpartum period and 1 case was pregnant. 1 patient had protein C deficiency, 1 had activated protein C resistancy, 1 had antithrombin III deficiency, 1 had anticardiolipin antibody positivity and 1 had thrombocytosis. There was no etiological resason in 4 of the cases and 1 patient could not be investigated because of the death of the patient in the early period. 9 patients recovered completely, 3 patients recovered partially and 2 patients had permanent visual loss.

CONCLUSION: CONCLUSION: Cerebral venous thrombosis needs highly suspection in order to define the clinical signs. As the early treatment prevents exitus and severe disability, early diagnosis is very important.