A Case Followed as Having Multiple Sclerosis but Diagnosed with Secondary Brain Lymphoma

Serkan Demir; Rıfat Erdem Toğrol; Ali&775; Rıza Sonkaya; Tolga Tuncel

doi:10.4274/tnd.70845

Serkan Demir¹, Rıfat Erdem Toğrol¹, Ali&775; Rıza Sonkaya¹, Tolga Tuncel²

¹Department Of Neurology, Gata Haydarpasa Training Hospital, Istanbul, Turkey
²Department Of Oncology, Gata Haydarpasa Training Hospital, Istanbul, Turkey

Keywords: Non-Hodgkin Lymphoma, Multiple Sclerosis, Nephrotic Syndrome

Abstract

Secondary brain lymphoma is more common than primary cases and usually presented with leptomeningeal lesions. Involvement of brain parenchyma is rare and brain metastases like secondary CNS lymphoma are occasionally confused with multiple sclerosis (MS) due to their localization and clinical presentation. The patient who has been followed with a diagnosis of MS was diagnosed with B-cell Non-Hodgkin Lymphoma after renal biopsy 1 year after occurance of MS symptoms which she consulted our department with cerebellar syndrome findings and found to have nephrotic syndrome. Hence her cranial lesions were regarded as secondary brain lymphoma. After initiation of chemotherapy, her lesions alleviated. The case was considered valuable to present because of the good response to chemotherapy and the probability to be confused with MS.