Lhermitte-Duclos Disease with Orthostatic Hypotension
Nesrin Helvacı Yılmaz1, Mehmet Şeker2, Mehmet Onur Omaygenç3, Umut Yaka4, Nazan Eryiğit5, Burak Yuluğ1
1Medipol University Faculty of Medicine, Department of Neurology, İstanbul, Turkey
2Medipol University Faculty of Medicine, Department of Radiology, İstanbul, Turkey
3Medipol University Faculty of Medicine, Department of Cardiology, İstanbul, Turkey
4Medipol University Faculty of Medicine, Department of Neurosurgery, İstanbul, Turkey
5Çakmak Erdem Hospital, Clinic of Neurosurgery, İstanbul, Turkey
Keywords: Lhermitte-Duclos disease, orthostatic hypotension, cerebellum
Abstract
Lhermitte-Duclos disease is a rare cerebellar dysplastic gangliocytoma. The most common symptoms include headache, nausea, vomiting, blurred vision, and imbalance. The typical appearance on cranial magnetic resonance imaging is hyper-intensity on T2-weighted images and hypo-intensity on T1-weighted images. The disease generally presents with benign progress. Development of obstructive hydrocephalus is an indication for urgent surgical intervention and surgery outcomes are satisfactory. Orthostatic hypotension is a very rare clinical presentation of this syndrome and ours is the second case of orthostatic hypotension to be reported in the literature.