Familial syringomyelia: Incidental or hereditary?

Abstract

Syringomyelia is a rare disease of the spinal cord, and its familial occurrence is even rarer. Both genetic and environmental factors appear to be involved in familial syringomyelia. Herein, we presented a 51-year-old father and his 18-year-old son with clinically and radiologically proven syringomyelia without Chiari malformation type 1. Both had a trauma history, which could render them prone to the development of syringomyelia; however, the presence of another affected individual in the family history suggests that genetic predisposition plays a more important role in the pathogenesis of this condition. Only one previous report of familial syringomyelia originated from Türkiye, with ours being the second.

Cite this article as: Demirci S, Doğan Ünlü M. Familial syringomyelia: Incidental or hereditary?. Turk J Neurol 2025;31(1):80-86. doi: 10.55697/tnd.2025.228.

The data that support the findings of this study are available from the corresponding author upon reasonable request.

Idea/concept, analysis and/ or interpretation, writing the article, other, design, materials, data collection and/or processing, references and fundings, literature review: S.D., M.D.Ü.; Control/ supervision, critical review: S.D.

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

The authors received no financial support for the research and/or authorship of this article.