Scale consistance in cognitive status awareness of patients with Parkinson’s disease
Sabiha Tezcan Aydemir1
, Elif Yüsra Unutmaz2, Pınar Özkan3, Talha Abalı3, Gülnur Ayık2, Dudu Genç Batmaz2, Sema Nur Kibrit3, Ahmet Veli Karacan3, Müge Kuzu Kumcu4, Merve Koç Yekedüz5, Fatma Tuba Eminoğlu5, Rezzak Yılmaz2,6, Muhittin Cenk Akbostancı2,6
1Department of Neuroscience, Bilkent Aysel Sabuncuoğlu National Manyetic Resonance Research Center, Ankara, Türkiye
2Department of Neurology, Ankara University Faculty of Medicine, Ankara, Türkiye
3Ankara University Faculty of Medicine, Ankara, Türkiye
4Department of Neurology, Lokman Hekim Faculty of Medicine, Ankara, Türkiye
5Department of Pediatrics, Division of Pediatric Metabolism, Ankara University Faculty of Medicine Ankara, Türkiye
6Department of Neuroscience, Ankara University Brain Research Center, Ankara, Türkiye
Keywords: Cognitive disorders in Parkinson’s disease, Parkinson’s disease dementia, the awareness of symptoms in Parkinson’s disease.
Abstract
Objectives: This study aimed to investigate the relationship between patients’ awareness of their cognitive symptoms and the presence of cognitive involvement according to neuropsychological tests.
Patients and methods: In this cross-sectional study, 539 patients (276 males, 263 females; mean age: 64.3±11.0 years; range, 19 to 88 years) were assessed between September 2020 and June 2023. The Mini-Mental Status Examination (MMSE) scores were recorded in addition to age, sex, education level, and chronic diseases. Patients were classified as having cognitive disorders if their MMSE scores were <26, while those with scores ≥26 were classified as cognitively healthy. The relationship between the frequency of cognitive involvement according to a related question from the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) and the frequency of cognitive disorders according to the MMSE scores was evaluated.
Results: No relationship was detected between the frequency of cognitive disorders according to the MMSE scores and the frequency of cognitive involvement according to the corresponding question in the nonmotor component of the MDS-UPDRS (p<0.001).
Conclusion: The findings indicate that the cognitive impairment inquiry in the nonmotor section of the MDS-UPDRS is not an effective method for detecting cognitive involvement in Parkinson’s disease.
Cite this article as: Tezcan Aydemir S, Unutmaz EY, Özkan P, Abalı T, Ayık G, Genç Batmaz D, et al. Scale consistance in cognitive status awareness of patients with Parkinson’s disease. Turk J Neurol 2024;30(3):185-189. doi: 10.55697/tnd.2024.139.
The data that support the findings of this study are available from the corresponding author upon reasonable request.
The study protocol was approved by the Ankara University Faculty of Medicine Ethics Committee (date: 25.11.2021, no: İ10-649-21). The study was conducted in accordance with the principles of the Declaration of Helsinki.
A written informed consent was obtained from each patient.
Idea/consept, design: S.T.A., R.Y., M.C.A.; Control/supervision: R.Y., M.C.A.; Data collection and processing: S.T.A., E.Y.U., P.Ö., T.A., G.A., D.G.B., S.N.K., A.V.K., M.K.Y., F.T.E., R.Y., M.C.A.; Analysis and interpretation: S.T.A., M.K.K., R.Y., M.C.A.; Literature review, writing the article: S.T.A.; Critical review: R.Y., M.C.A.
The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
The authors received no financial support for the research and/or authorship of this article.