Neuromyotonia and Epilepsy: Case Report

Abstract

Neuromyotonia is a rare clinical syndrome of spontaneously occurring muscle activity of distal peripheral nerve origin . Although neuromyotonia sometimes inherited, most cases are acquired. Here, we report a case of 21 years old girl with typical clinical and electromyographic findings of neuromyotonia who also had epilepsy. Her family first realized the existence of this muscle activity as early as she was 2 years old, which is stated to be continued in a slowly progressive fashion. She had myokymia consisting of continuous, undulating, irregular, asynchronous and slow muscular contractions in bilateral quadriceps muscles. There were irregular doublet, triplet or multiplet motorunit discharges in electromyographic examination. We performed epidural and femoral nerve block. We found that spontaneous muscle discharges completely abolished after femoral and epidural nerve blocks. Because of having neuromyotonia of proximal nerve origin, as well as epilepsy, this particular case was briefly discussed.