Mechanisms of myelinization, demyelinization and remyelinization
Ayşe ALTINTAŞ, Gülçin BENBİR
İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi Nöroloji Anabilim Dalı, İSTANBUL
Keywords: lumbar puncture, leptomeningeal carcinomatosis, CSF cytological examination
Abstract
Myelination in the central nervous system which is formed by specialized processes of the plasma membranes of oligodendrocytes, should be understood well, in order to comprehend the pathophysiology of diseases characterised by demyelination. in this article, we reviewed the embryonic development and differentiation of the oligodendrocytes, axonal myelination, structure of the myelin and the factors playingrole in the regulation and maintenance of the myelination.