Side Effects of Intravenous Immunoglobulin Treatment in Neurological Disorders

Buket Oflazoğlu, Fatma Öztürk, Hatice Kayaalp Açık, Çağatay Öncel, Ülker Anadol, Hulki Forta

Neurology Clinic 1, Sisli Etfal Hospital, İstanbul, Turkey

Keywords: intravenous immunoglobulin, side effects

Abstract

OBJECTIVE: In general, adverse reactions to Intravenous

Immunoglobulin therapy are usually minör and occur in %1-81 of

patients, serious side effects are less such as hemolysis, thrombosis,

anaphylaxis.

METHODS: We aimed to report the side effects of Intravenous

Immunoglobulin therapy, especially hemolysis, thrombosis in our clinic

RESULTS: 52 hospitalized patients with neurologic

diseases were subject of this survey and followed as side effects during

and after infusion.

CONCLUSION: Adverse reactions were observed in our total 7 patients, serious

side effect as hemolysis and thromboembolism was observed in our 3

patients.