Cerebral Vein and Sinus Thrombosis: Clinical Evaluation

Abstract

Cerebral Vein and Sinus Thrombosis: Clinical Evaluation Scientific background: Cerebral venous thrombosis may mimic many other neurological diseases clinically. Severe changes in consciousness and moderate focal neurological deficits could be seen. The syndrome may also be presented with subclinic, slowly progressive and soft neurological symptoms such as headache. The diagnosis is difficult because the initial computerized tomography is usually normal or the signs are not noticeable. It may be mortal or cause morbidity if the treatment is delayed. Objectives: In this study, we defined the clinical features and radiological findings of patients who have taken the diagnosis of cerebral venous sinus thrombosis. In the aspect of the present literature, clinical approach to Cerebral Sinus Thrombosis is discussed. Patients and Method: This is a retrospective study including 18 patients having the diagnosis of Cerebral Vein and Sinus Thrombosis in our clinic. The patient records and neuroradiology archives of the patients are evaluated. Results: The most common symptom was headache and the most common finding was papillaedema. The mortality rate was 11.11%. The most frequently affected sites were superior sagittal, sigmoid and transverse sinuses. Pregnancy andn lupus anticoagulant were the most common precipitating conditions. Conclusion: Cerebral Sinus Thrombosis may present with mild symptoms and findings. The first step diagnostic procedure is Magnetic Resonance imaging and MR Venography. The anticipating thrombophilic and systemic diseases should be investigated. If necessary, anticoagulant therapy is reliable and beneficial.