Intravenous Immunoglobulin Use in A Case of Acute Disseminated Encephalomyelitis with Concomittant Motor Axonal Neuropathy

Çağatay Öncel; Yılmaz Kıroğlu; Selahattin Gür

Çağatay Öncel¹, Yılmaz Kıroğlu², Selahattin Gür¹

¹Department Of Neurology, Pamukkale University, Faculty Of Medicine, Denizli, Turkey
²Department Of Radiology, Pamukkale University, Faculty Of Medicine, Denizli, Turkey

Keywords: ADEM, axonal neuropathy, intravenous immunglobulin

Abstract

Scientific BACKGROUND: Acute disseminated encephalomyelitis (ADEM) is an acute widespread demyelinating condition, which affects brain and spinal cord usually after vaccination or viral infection. Diagnosis is made by cranial imaging, lumbar puncture and presence of myelin basic protein. The classic treatment for ADEM consists of IV administration of steroids.

OBJECTIVES: Recently, there have been been few publications concerning the successful use of IV immunglobulins (IVIG) in ADEM. Here, we report a case of steroid resistent ADEM in a patient with acute axonal motor neuropathy, she was treated succesfully with IVIG.

CONCLUSION: Acute disseminated encephalomyelitis with acute motor axonal neuropathy has been reported by now in two patients.