Paraneoplastic Encephalitis Associated with Anti-Ma2 Antibodies and Mesothelioma-Like Poorly Differentiated Lung Cancer

Can Ebru Bekircan; Amber Eker; Öztürk Ateş; Kader Karlı Oğuz

Can Ebru Bekircan¹, Amber Eker¹, Öztürk Ateş², Kader Karlı Oğuz³

¹Faculty Of Medicine, University Of Hacettepe, Department Of Neurology, Ankara, Turkey
²Faculty Of Medicine, University Of Hacettepe, Department Of Internal Medicine, Ankara, Turkey
³Faculty Of Medicine, University Of Hacettepe, Department Of Radiology, Ankara, Turkey

Keywords: Mesothelioma, limbic encephalitis, encephalitis, paraneoplastic syndromes

Abstract

We report a case of paraneoplastic encephalitis associated with anti-Ma2 antibodies. Medical history and thorax computed tomog-

raphy findings suggested malignant mesothelioma. Pleural biopsy results were compatible with high-grade neoplastic infiltration. Alt-

hough the biopsy could not differentiate the type of neoplasm, mesothelioma was considered a strong possibility in this poorly dif-

ferentiated lung carcinoma. To the best of our knowledge this is the first case report of paraneoplastic encephalitis associated with

anti-Ma2 antibodies and mesothelioma.