Double Filtration Plasmapheresis in the Treatment of a Case with Acute Disseminated Encephalomyelitis

Mehmet Uğur Çevik; Mehmet Guli Çetinçakmak; Sefer Varol; Eşref Akıl

doi:10.4274/Tnd.39206

Mehmet Uğur Çevik¹, Mehmet Guli Çetinçakmak², Sefer Varol², Eşref Akıl²

¹Department Of Neurology, Faculty Of Medicine, University Of Dicle, Diyarbakır, Turkey
²Department Of Radiology, Faculty Of Medicine, University Of Dicle, Diyarbakır, Turkey

Keywords: Acute disseminated encephalomyelitis, corticosteroids, double filtration plasmapheresis

Abstract

Acute disseminated encephalomyelitis (ADEM), is a monophasic autoimmune demyelinating disease of the central nervous system. Although high-dose steroid

management has been considered the mainstay of treatment for ADEM, some patients are unresponsive to steroid therapy. We report the case of a 44-year-old

woman with ADEM who did not respond to steroid therapy, but who showed a noticeable improvement with double filtration plasmapheresis (DFPP). To the best

of our knowledge, this is the first case report of ADEM in literature treated with DFPP. (Turkish Journal of Neurology 2013; 19: 63-5)