Ischemic stroke as initial manifestation of Takayasu arteritis: A case series

Mohammad Kurniawan, Nadira Deanda Putri, Salim Harris, Al Rasyid, Taufik Mesiano, Rakhmad Hidayat

Department of Neurology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

Keywords: Diagnosis, ischemic stroke, stroke, Takayasu arteritis.

Abstract

Takayasu arteritis (TAK) is a rare, chronic inflammatory disease involving large blood vessels, particularly the aorta and its branches. This case report is noteworthy due to its unusual presentation with ischemic stroke in a young adult, highlighting the importance of considering this diagnosis in similar clinical scenarios to improve patient outcomes. In Case 1, a 38-year-old male with right-sided hemiparesis and a history of leg pain underwent imaging, revealing ischemic stroke, subsequently confirmed as TAK. Case 2 involved an 18-year-old female with recurrent strokes, cramps, and leg pain, leading to the diagnosis of TAK. Both patients received corticosteroids, antiplatelets, and other therapies, resulting in symptomatic relief. This case series emphasized the need for healthcare professionals to consider TAK in young stroke patients for timely diagnosis and multidisciplinary management. The absence of specific treatment guidelines highlights the necessity for larger prospective studies to guide effective treatment strategies in TAK patients with stroke.

Cite this article as: Kurniawan M, Putri ND, Harris S, Rasyid A, Mesiano T, Hidayat R. Ischemic stroke as initial manifestation of Takayasu arteritis: A case series. Turk J Neurol 2025;31(2):232-241. doi: 10.55697/tnd.2025.276.

Data Sharing Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.

Author Contributions

Idea, concept: M.K.; Design, literature review: M.K., N.D.P.; Control/supervision: M.K., S.H., A.R.; Data collection and or processing: M.K., N.D.P., T.M., R.H.; Analysis and/or interpret: M.K., T.M., R.H.; Writing: M.K., N.D.P.; Critical review: M.K., S.H., A.R.; References: M.K., N.D.P.; Materials: M.K., N.D.P., T.M., R.H.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/ or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.