e-ISSN 1309-2545      ISSN 1301-062X
TR    ENG
 

Download Current Issue.

Volume : 28 Issue : 2 Year : 2022

Current Issue Archive Popular Articles Ahead of Print Submit Your Article Login Copyright Transfer Form
Turkish Journal of Neurology Indexed By
  The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease [Turk J Neurol]
Turk J Neurol. 2022; 28(2): 84-90 | DOI: 10.4274/tnd.2022.99836  

The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease

Fatih Söke1, Elvan Özcan Gülşen2, Nigar Esra Erkoç Ataoğlu3, Çağrı Gülşen4, Bilge Koçer5, Ayçe Bora Tokçaer3
1University of Health Sciences Turkey, Gulhane Faculty of Physiotherapy and Rehabilitation, Department of Neurological Physiotherapy-Rehabilitation, Ankara, Turkey
2Anadolu University Yunus Emre Vocational School of Health Services, Elderly Care Program, Eskisehir, Turkey
3Gazi University Faculty of Medicine, Department of Neurology, Ankara, Turkey
4Gazi University Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Ankara, Turkey
5University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital, Clinic of Neurology, Ankara, Turkey

Objective: Although impaired manual dexterity is one of the most disabling symptoms in patients with Parkinson’s disease (PD), there is no reliable and valid patient-reported outcome measure (PROM) for assessing dexterity. Therefore, this study aimed to investigate: (1) The test-retest reliability of the manual ability measure-36 (MAM-36) in patients with PD; (2) the minimum detectable change (MDC) in the MAM-36 scores; (3) the concurrent and known-groups validity of the MAM-36 scores; and (4) the cut-off score that best discriminates patients with PD from healthy individuals.
Materials and Methods: This was a cross-sectional study. The MAM-36 was repeated after 4 weeks to determine the test-retest reliability which was calculated with the intraclass correlation coefficient (ICC), Bland-Altman plots, and MDC. The concurrent validity was assessed using correlations between the MAM-36 and nine-hole peg test, Movement Disorders Society Unified Parkinson’s Disease Rating scale (MDS-UPDRS), MDS-UPDRS II, MDS-UPDRS III, Hoehn and Yahr stage, and 8-item PD questionnaire. The known-groups validity was determined by comparing the MAM-36 scores between patients with PD and healthy individuals. Receiver operating characteristic analysis was used to determine the cut-off score for the MAM-36 to best discriminate patients with PD from healthy individuals.
Results: Thirty six patients with PD and 32 healthy individuals were included. Excellent test-retest reliability was found (ICC: 0.953). The Bland-Altman plot demonstrated a high agreement. The MDC was 2.33. The MAM-36 had fair to high correlations with the other outcome measurements (correlation coefficients ranged from -0.473 to -0.763, p<0.05 for all). Patients with PD had lower scores than healthy individuals in terms of the MAM-36 (p<0.001). The cut-off score of 76.50 best distinguished patients with PD from healthy individuals.
Conclusion: The MAM-36 is a reliable and valid measurement for assessing manual dexterity in patients with PD. It is also the only clinically available PROM in assessing manual dexterity for patients with PD in the Turkish population.

Keywords: Manual ability measure-36, manual dexterity, Parkinson’s disease, reliability, validity


Fatih Söke, Elvan Özcan Gülşen, Nigar Esra Erkoç Ataoğlu, Çağrı Gülşen, Bilge Koçer, Ayçe Bora Tokçaer. The Reliability and Validity of the Manual Ability Measure-36 in Patients with Parkinson’s Disease. Turk J Neurol. 2022; 28(2): 84-90

Corresponding Author: Fatih Söke, Türkiye


TOOLS
English Full Text
Print
Download citation
RIS
EndNote
BibTex
Medlars
Procite
Reference Manager
Share with email
Share
Send email to author

Similar articles
PubMed
Google Scholar




 
© Copyright 2022 Turkish Journal of Neurology
Home        |        Contact
LookUs & OnlineMakale