Reversible Posterior Leucoencephalopathy (PLES) Syndrome

Reversible Posterior Leucoencephalopathy (PLES) Syndrome
Scientific background: The posterior leucoencephalopathy (PLES) is a
clinico-radiological syndrome characterised by headache, nausea,
vomiting, disturbances in cognition, depressed level of consciousness,
visual abnormalities and convulsions. It is commonly associated with
malignant hypertension, toxemia of pregnancy or use of
immunosuppressive agents.
O b j e c t i v e: We, here, report a case of reversible posterior
leucoencephalopathy syndrome in a patient submitted with headache,
hypertension, quadranopia and the importance of performing cranial
imaging and the benefit of diffusion MRI in the differential diagnosis of
P L E S.
F i n d i n g s: MRI and diffusion MRI studies have been performed in a 35
year old male patient with hypertension and renal failure, and diffuse
posterior system lesions have been found.
C o n c l u s i o n: The patient’s clinical and radiologic recovery occurs
following control of blood pressure.