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  The Role of Hyperhomocysteinemia in İschemic Stroke [Turk J Neurol]
Turk J Neurol. 1999; 5(2): 115-119

The Role of Hyperhomocysteinemia in İschemic Stroke

Şeref DEMİRKAYA1, Okay VURAL1, Ahmet AYDIN2, Zeki GÖKÇİL1, M. Akif TOPÇUOĞLU3, Aşkın IŞIMER2
1GATA Nöroloji Anabilim Dalı, Ankara
2GATA Farmakoloji Anabilim Dalı, Ankara
3Mevki Asker Hastanesi, Ankara

It was shown that hyperhomocysteinemia is a risk factor premature atherosclerosis and vascular occlusive disease. To determine whether byperbomocysteiııemia is a risk factor for ischemic stroke, plasma homocystein levels were measured in 155 stroke patients and 40 control subjects. The mean plasma homocystein level was 21.84±8.5 µmol/l in stroke patients and 1032 ± 4.28 µmol/l in control group. Difference between two groups was significant (p<0.001). Additionally, we couldn't detect any risk factor except hyperhomocysteinemia in 9 patients with stroke. Results of this study indicate thatmild or moderate hyperhomocysteinemia might be a risk factor for stroke.

Keywords: Homocystein, ischemic stroke, risk


Şeref DEMİRKAYA, Okay VURAL, Ahmet AYDIN, Zeki GÖKÇİL, M. Akif TOPÇUOĞLU, Aşkın IŞIMER. The Role of Hyperhomocysteinemia in İschemic Stroke. Turk J Neurol. 1999; 5(2): 115-119

Corresponding Author: Şeref DEMİRKAYA


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