Investigation of Genetic Characteristics of Glial Tumors

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Volume : 28 Issue : 4 Year : 2022

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Turkish Journal of Neurology Indexed By

Investigation of Genetic Characteristics of Glial Tumors [Turk J Neurol]

Turk J Neurol. 1999; 5(2): 92-94

Investigation of Genetic Characteristics of Glial Tumors

E. O�UL¹, S. AK�ALAR², E. KORFALI³, A. BEKAR⁴, �. TOLUNAY⁵, F. TURAN¹, S. ARTAN⁶
¹Uluda� �niversitesi T�p Fak�ltesi N�roloji Anabilim Dal�, Bursa
²Uluda� �niversitesi T�p Fak�ltesi Mikrobiyoloji Anabilim Dal� Genetik Laboratuar�, Bursa
³Uluda� �niversitesi T�p Fak�ltesi N�ro�irurji Anabilim Dal�, Bursa
⁴Uluda� �niversitesi T�p Fak�ltesi N�ro�irurji Anabilim Dal�, Bursa
⁵Uluda� �niversitesi T�p Fak�ltesi Patoloji Anabilim Dal�, Bursa
⁶Osmangazi �niversitesi T�p Fak�ltesi GENTAM, Eski�ehir

In this study, 35 glial tumors diagnosed by CT, MR and histopathologically, were investigated for chromosomal aberration by caryotip analysis on tumor culture. In addition, p53 gene mutation was investigated by FISH techniqe on 6 glial tumors. l7p deletion was found on 21 cases. Besides monosomi was shown on chromosome 22, 10 and 9.P53 gene mutation was found by FISH tecnique on 4 of 6 glial tumor.

Keywords: Glial tumors, tumor tissue culture, chromosomal investigation

E. O�UL, S. AK�ALAR, E. KORFALI, A. BEKAR, �. TOLUNAY, F. TURAN, S. ARTAN. Investigation of Genetic Characteristics of Glial Tumors. Turk J Neurol. 1999; 5(2): 92-94

Corresponding Author: E. O�UL

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