Investigation of Genetic Characteristics of Glial TumorsE. OĞUL1, S. AKÇALAR2, E. KORFALI3, A. BEKAR4, Ş. TOLUNAY5, F. TURAN1, S. ARTAN61Uludağ Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı, Bursa
2Uludağ Üniversitesi Tıp Fakültesi Mikrobiyoloji Anabilim Dalı Genetik Laboratuarı, Bursa
3Uludağ Üniversitesi Tıp Fakültesi Nöroşirurji Anabilim Dalı, Bursa
4Uludağ Üniversitesi Tıp Fakültesi Nöroşirurji Anabilim Dalı, Bursa
5Uludağ Üniversitesi Tıp Fakültesi Patoloji Anabilim Dalı, Bursa
6Osmangazi Üniversitesi Tıp Fakültesi GENTAM, Eskişehir
In this study, 35 glial tumors diagnosed by CT, MR and histopathologically, were investigated for chromosomal aberration by caryotip analysis on tumor culture. In addition, p53 gene mutation was investigated by FISH techniqe on 6 glial tumors. l7p deletion was found on 21 cases. Besides monosomi was shown on chromosome 22, 10 and 9.P53 gene mutation was found by FISH tecnique on 4 of 6 glial tumor. Keywords: Glial tumors, tumor tissue culture, chromosomal investigation
E. OĞUL, S. AKÇALAR, E. KORFALI, A. BEKAR, Ş. TOLUNAY, F. TURAN, S. ARTAN. Investigation of Genetic Characteristics of Glial Tumors. Turk J Neurol. 1999; 5(2): 92-94
Corresponding Author: E. OĞUL |
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