Dyke Davidoff Masson Syndrome With Crossed Cerebellar Atrophy: A Case Report And Review Of The Literature

Dyke Davidoff Masson Syndrome (DDMS) is characterized clinically by hemiplegia or hemiparesis, mental retardation, epilepsy and radiologically by cerebral hemiatrophy, ipsilateral calvarial thickening, dilation of the ipsilateral sinuses, and increased aeration. Atrophy in the cerebral hemisphere may be accompanied by atrophy in the contralateral cerebellum. This condition is defined as cross cerebellar atrophy (CCA). Although CCA's pathogenesis is unclear, it has been associated with damage to the corticopontocerebellar pathways and neuronal connections connecting the cerebellum and contralateral cerebral hemisphere. Using diffusion tensor imaging (DTI) and conventional magnetic resonance imaging (MRI) methods may help to demonstrate axonal connection pathways and make a diagnosis. Here we present a 39-year old female patient with clinical and radiological findings of DDMS associated with CCA.