Asymmetrical Lobar Degenerations: Clinical, Neuropsychological, Scanning DataNeşe Tuncer, İpek Midi, Tülin Tanrıdağ, Aynur Mollahasanoğlu, Özen Çatan, Önder UsDepartment Of Neurology, Marmara University, Faculty Of Medicine, İstanbul, Turkey
OBJECTIVE: Asymmetric lobar degenerations are clinical syndromes which affect primarily one or more than one cerebral lobe and result progressive language and/or behaviour and/or cognitive dysfunction. METHODS: We report the clinical, neuropsychological and neuroimaging results of 5 patients with asymmetric lobar degeneration an one or more than one clinical syndrome according to Frontotemporal Lobar Degeneration: A Consensus on Clinical Diagnostic Criteria. RESULTS: Asymmetric lobar degeneration may be one of the largest entities after Alzheimer Disease to cause dementia. Not only frontal lobe dementia but also progressive language disorder and corticobasal degeneration syndrome can be produced by frontotemporal lobar degeneration and both clinical and pathological overlap of the syndromes can be seen. The recognition of the relationship between the clinical syndromes has important implications in the diagnosis and treatment of dementias. CONCLUSION:
Keywords: Asymmetric lobar degeneration, frontal lobe dementia, progressive nonfluent aphasia, corticobasal degeneration syndrome, Pick Complex.
Neşe Tuncer, İpek Midi, Tülin Tanrıdağ, Aynur Mollahasanoğlu, Özen Çatan, Önder Us. Asymmetrical Lobar Degenerations: Clinical, Neuropsychological, Scanning Data. Turk J Neurol. 2006; 12(2): 112-120
Corresponding Author: Neşe Tuncer, Türkiye |
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