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Repetitive Transcranial Magnetic Stimulation in Patients with Hereditary Spastic Paraplegia [Turk J Neurol]
Turk J Neurol. 2011; 17(2): 119-121

Repetitive Transcranial Magnetic Stimulation in Patients with Hereditary Spastic Paraplegia

Mehmet Ağırman, Beyhan Eren, Evrim Karadağ Saygı
Marmara University School Of Medicine, Department Of Physical Medicine And Rehabilitation, Istanbul

Hereditary spastic paraplegia (HSPP) is a heterogeneous genetic disease characterized by progressive spasticity of lower extremities. Spasticity is a major cause of long-term disability in HSPP and significantly affects the functional life of patients. Repetitive transcranial magnetic stimulation (rTMS) is widely used in diagnosis and treatment of many neurological and psychiatric diseases. Although the positive impacts of rTMS for spasticity have been reported, no study has been found on HSPP. We present two HSPP patients treated with low frequency rTMS (20 minutes at a frequency of 1 Hz (1200 pulses), for a period of 10 treatment sessions).

Keywords: Hereditary spastic paraplegia, repetitive transcranial magnetic stimulation, spasticity


Mehmet Ağırman, Beyhan Eren, Evrim Karadağ Saygı. Repetitive Transcranial Magnetic Stimulation in Patients with Hereditary Spastic Paraplegia. Turk J Neurol. 2011; 17(2): 119-121

Corresponding Author: Evrim Karadağ Saygı, Türkiye


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