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The role of genetics in stroke risk factors; the discussion of two rare genetic syndroms associated with stroke and review of the literature [Turk J Neurol]
Turk J Neurol. 2015; 21(3): 104-109 | DOI: 10.4274/tnd.93824  

The role of genetics in stroke risk factors; the discussion of two rare genetic syndroms associated with stroke and review of the literature

Eda Kılıç Çoban, Nilüfer Kale İçen, Mesude Özerden Acar, Melek Çolak Atmaca, Aysun Soysal
Department Of 3rd Neurology, Bakırköy Research And Training Hospital For Psychiatry,neurology And Neurosurgery

Stroke is defined as a focal or at times global neurological impairment of sudden onset, that lasts more than 24 hours or that leads to death. The nonmodifiable risk factors for stroke include age, race, gender and acquired risk factors include smoking, hypertension, diabetes and obesity. Previous studies have shown that these mentioned risk factors might be responsible for approximately 50% of patients presenting stroke. However for the remaining half of the stroke patients no risk factors could be detected and genetics might be responsible for this group. In this manuscript we would like to present 2 cases who were being followed-up with the rare genetic syndromes as Marfan syndrome and Robinow syndrome respectively. These patients presented to our clinic with stroke and no identifiable risk factors other than these genetic syndromes could be detected. By this case-series we would like to further discuss the relationship between genetic syndromes and stroke.

Keywords: Marfan, Robinow, syndrome, stroke, genetics


Eda Kılıç Çoban, Nilüfer Kale İçen, Mesude Özerden Acar, Melek Çolak Atmaca, Aysun Soysal. The role of genetics in stroke risk factors; the discussion of two rare genetic syndroms associated with stroke and review of the literature. Turk J Neurol. 2015; 21(3): 104-109

Corresponding Author: Eda Kılıç Çoban, Türkiye


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