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From Bad to Worse: Intravenous Thrombolysis in Tandem Occlusion [Turk J Neurol]
Turk J Neurol. 2012; 18(4): 173-174 | DOI: 10.4274/Tnd.77044  

From Bad to Worse: Intravenous Thrombolysis in Tandem Occlusion

Serdar Tütüncü1, Annerose Ziegler1, Jochen Fiebach2, Heinrich Audebert1, Christian Nolte2
1Charite Universtiy Hospital, Department Of Neurology, Berlin, Germany
2Center For Stroke Research - Charite, Berlin, Germany

We report a stroke patient with tandem occlusion of both the distal middle cerebral artery (MCA) and the ipsilateral internal carotid artery (ICA) who clinically deteriorated after intravenous thrombolysis in spite of recanalization of the ICA because of new proximal MCA (main-stem) occlusion. We discuss this unfortunate course (clinical deterioration in spite of partial recanalization) in the light of the characteristics of human brain vasculature and argue in favour of a more aggressive reperfusion strategy in this special setting.

Keywords: Stroke, tandem occlusion, iv thrombolysis


Serdar Tütüncü, Annerose Ziegler, Jochen Fiebach, Heinrich Audebert, Christian Nolte. From Bad to Worse: Intravenous Thrombolysis in Tandem Occlusion. Turk J Neurol. 2012; 18(4): 173-174

Corresponding Author: Serdar Tütüncü, Germany


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