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Intravenous Thrombolytic Therapy in Acute Stroke: Problems and Solutions [Turk J Neurol]
Turk J Neurol. 2017; 23(4): 162-175 | DOI: 10.4274/tnd.71084  

Intravenous Thrombolytic Therapy in Acute Stroke: Problems and Solutions

Mehmet Akif Topçuoğlu1, Ethem Murat Arsava1, Atilla Özcan Özdemir2, Erdem Gürkaş3, Dilek Necioğlu Örken4, Şerefnur Öztürk5
1Hacettepe University Faculty of Medicine, Department of Neurology, Ankara, Turkey
2Osmangazi University Faculty of Medicine, Department of Neurology, Eskisehir, Turkey
3Gulhane Training and Research Hospital, Clinic of Neurology, Ankara, Turkey
4Istanbul Bilim University Faculty of Medicine, Department of Neurology, Istanbul, Turkey
5Selcuk University Faculty of Medicine, Department of Neurology, Konya, Turkey

Use of intravenous tissue plasminogen activator (tPA) is one of the key elements of acute ischemic stroke management. Its use has not become widespread, and has faced significant problems in our country for more than a quarter of a century most probably due to many unanswered questions about issues related with daily practice. However, recent developments, which adequately focused and found solutions for most of these problems and questions, have led to a major change of point of view and understanding of the hyperacute management of stroke. This article, in the light of the relevant literature, discusses and provides clear recommendations for questions directed by neurologists practicing in Turkey mainly about typical neurologic issues faced in the setting of tPA use for acute stroke.

Keywords: Stroke, thrombectomy, contraindication, avoidance, training


Mehmet Akif Topçuoğlu, Ethem Murat Arsava, Atilla Özcan Özdemir, Erdem Gürkaş, Dilek Necioğlu Örken, Şerefnur Öztürk. Intravenous Thrombolytic Therapy in Acute Stroke: Problems and Solutions. Turk J Neurol. 2017; 23(4): 162-175

Corresponding Author: Mehmet Akif Topçuoğlu, Türkiye


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