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A Case of Senile Chorea: Considering Huntington’s Disease and Neuroacanthocytosis in differential diagnosis [Turk J Neurol]
Turk J Neurol. 2015; 21(3): 119-123 | DOI: 10.4274/tnd.34545  

A Case of Senile Chorea: Considering Huntington’s Disease and Neuroacanthocytosis in differential diagnosis

Ayşe Deniz Elmalı1, Ayşegül Gündüz1, Zafer Başlar2, Fatoş Sibel Ertan1
1Istanbul University, Cerrahpasa Medical Faculty, Department Of Neurology
2Istanbul University, Cerrahpasa Medical Faculty, Department Of Internal Medicine, Division Of Hematology

Sporadic chorea presenting after the age of 50 is called “senile chorea”. Senile chorea is a rare entity with a wide differential diagnosis list. Causes of senile chorea include vascular and metabolic diseases, adverse events related to medications, hematologic and immune system diseases, genetic and sporadic neurodegenerative syndromes, and paraneoplastic disorders. Although the most common etiologies are vascular and metabolic disorders, neuroacanthocytosis, Wilson and Huntington diseases are included in the differential diagnosis.
Here, we discuss differential diagnosis and approach to late onset chorea based on a case with late onset chorea, whose clinical findings suggested chorea-acanthocytosis at first, but revealed to be Huntington disease after detailed laboratory studies.

Keywords: chorea, senile chorea, Huntington Disease, chorea-acanthocytosis, neuroacanthocytosis


Ayşe Deniz Elmalı, Ayşegül Gündüz, Zafer Başlar, Fatoş Sibel Ertan. A Case of Senile Chorea: Considering Huntington’s Disease and Neuroacanthocytosis in differential diagnosis. Turk J Neurol. 2015; 21(3): 119-123

Corresponding Author: Ayşe Deniz Elmalı, Türkiye


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