e-ISSN 1309-2545      ISSN 1301-062X
TR    ENG
 

Download Current Issue.

Volume : 25 Issue : 2 Year : 2019

Current Issue Archive Popular Articles Ahead of Print Submit Your Article Login
Turkish Journal of Neurology Indexed By
 
  Search






Factors associated with prognosis in patients with Guillain Barre Syndrome [Turk J Neurol]
Turk J Neurol. Ahead of Print: TJN-34445

Factors associated with prognosis in patients with Guillain Barre Syndrome

Mustafa Çetiner1, Murat Seyit2, Gönül Akdağ3, Hayri Demirbaş4, Özge Temel1, Sibel Canbaz Kabay1
1Kütahya Health Sciences University Faculty of Medicine, Department of Neurology, Kütahya
2Kütahya Evliya Celebi Teaching and Research Hospital, Department of Emergency Medicine, Kütahya
3Kütahya Evliya Celebi Teaching and Research Hospital,Department of Neurology, Kütahya
4Afyonkarahisar Health Sciences University Faculty of Medicine, Department of Neurology, Afyonkarahisar

Objective: We aimed to evaluate the demographic, clinical, laboratory and electrophysiological findings of patients with inpatient Guillain-Barré syndrome in our clinics and to investigate the effect of these parameters on the prognosis of the disease.
Materials and Methods: Between January 2014 and April 2018, file records of patients admitted to our clinics with the diagnosis of Guillain Barre syndrome were retrospectively reviewed. Demographic characteristics, clinical, laboratory and electrophysiological findings of the patients at the time of admission were recorded. Patients were clinically graded according to the HUGHES classification at the time of admission and on the 3rd month after discharge.
Results: In the study, 25 of the 51 patients were male (49%) and 26 were female (51%) and the mean age was 54,21 ± 17,32 years. According to clinical and electrophysiologic diagnosis, 34 patients (66.7%) had acute inflammatory cardiomyopathy, 9 patients (17.6%) had acute motor axonal neuropathy, 6 patients (11.8%) had acute motor sensory axonal neuropathy and 2 patients (3.9%) had Miller Fisher syndrome. According to Hughes scoring on the 3rd month after discharge, 31 patients (60.8%) had in good prognosis (HUGHES score ≤2) and 20 patients (39.2%) had in poor prognosis group (HUGHES score> 2). In the comparison between the two groups according to clinical, demographic, and laboratory parameters, older age (≥50), high HUGHES score at admission, weakness in extremities as first complaint, the presence of complications, need for mechanical ventilation and presence of gastroenteritis as a leading infection were evaluated as prognostic factors.
Conclusion: The most common variant of Guillain-Barre syndrome in our study was acute inflammatory demyelinating polyradiculoneuropathy. Older age (≥50), high Hughes score at admission, weakness in extremities as first complaint, presence of complications, need for mechanical ventilation and presence of gastroenteritis as a precursor infection were poor prognostic factors.

Keywords: Guillain Barre syndrome, clinical findings, prognosis.




Corresponding Author: Mustafa Çetiner, Türkiye


TOOLS
Uncorrected Full Text PDF
Print
Download citation
RIS
EndNote
BibTex
Medlars
Procite
Reference Manager
Share with email
Share
Send email to author

Similar articles
PubMed
Google Scholar




 
© Copyright 2019 Turkish Journal of Neurology
Home        |        Contact
LookUs & OnlineMakale