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Turkish Journal of Neurology Indexed By
  A Rare Cause of Headache and Increased Intracranial Pressure: Primary Leptomeningeal Melanomatosis [Turk J Neurol]
Turk J Neurol. 2014; 20(4): 138-140 | DOI: 10.4274/tnd.26122  

A Rare Cause of Headache and Increased Intracranial Pressure: Primary Leptomeningeal Melanomatosis

Aslan Tekataş1, Yağmur İ. Gemici1, Sedat Alpaslan Tuncel2, Bekir Çağlı2, Ebru Taştekin3, Ercüment Ünlü2, Yahya Çelik1
1Trakya University, Medicine Faculty, Department Of Neurology
2Trakya University, Medicine Faculty, Department Of Radiology
3Trakya University, Medicine Faculty, Department Of Patology

Primary leptomeningeal melanomatosis is a rare central nervous system neoplasm originating from leptomeningeal melanocytes. The cases can be presented with focal neurologic deficit, seizure, neuropsychiatric symptoms or increased intracranial pressure symptoms along with encephalitis or meningitis. Diagnosis can be made upon imaging studies, cytopathologic examination of cerebrospinal fluid and biopsy. Biopsy can return false negative since the leptomeningeal involvement is not diffuse. In this study, a case is presented who admitted to hospital with leptomenengitis symptoms such as headache, fever and altered state of consciousness and developed additional neurologic signs after months. First biopsy came out as normal while the second one did as positive. This case has been found worth presenting since this is a tumor of rare existence and the diagnosis was made upon the second biopsy.

Keywords: Primary leptomeningeal melanoma, Headache, Increased intracranial pressure, Leptomenengitis


Aslan Tekataş, Yağmur İ. Gemici, Sedat Alpaslan Tuncel, Bekir Çağlı, Ebru Taştekin, Ercüment Ünlü, Yahya Çelik. A Rare Cause of Headache and Increased Intracranial Pressure: Primary Leptomeningeal Melanomatosis. Turk J Neurol. 2014; 20(4): 138-140

Corresponding Author: Aslan Tekataş, Türkiye


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