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Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders [Turk J Neurol]
Turk J Neurol. 2012; 18(4): 155-161 | DOI: 10.4274/Tnd.26097  

Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders

Arzu Çoban1, Zeliha Matur2, Haşmet A. Hanağası2, Yeşim Parman2
1Department Of Neurology, Balıkesir University Medical Faculty, Balıkesir, Turkey
2Department Of Neurology, Istanbul University, Istanbul Medical Faculty,ıstanbul, Turkey

OBJECTIVE: Local injection of botulinum toxin is a highly effective treatment option for a wide range of movement disorders and there are reliable sources of information on its indications, effects and safety in clinical practice. In this study, we report our experience with botulinum toxin in the treatment of facial region disorders.
METHODS: Patients who had been followed in the Botulinum Toxin Outpatient Clinic of the Neurology Department were retrospectively evaluated. Two preparations of botulinum toxin type A (BT-A) were used. The efficacy of BT-A injections was rated according to the improvement in symptoms as follows: marked - 75-100% improvement, good - 50-74%, moderate - 25-49%, and insufficient - less than 25% symptom relief.
RESULTS: One hundred eighty-two patients (73 male, 109 female) with various facial region disorders were included. The efficacy rates for patients who had very good and good improvement were high in the treatment of blepharospasm, hemifacial spasm, facial synkinesis, and Meige syndrome and moderate for oromandibular dystonia and hypersalivation. Ptosis was the most common side effect.
CONCLUSION: According to our results, botulinum toxin was very effective treatment for blepharospasm, Meige syndrome, hemifacial spasm and facial synkinesis, whereas it demonstrated good efficacy in oromandibular dystonia and hypersalivation.

Keywords: Botulinum toxin type-A, facial region disorders, efficacy


Arzu Çoban, Zeliha Matur, Haşmet A. Hanağası, Yeşim Parman. Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders. Turk J Neurol. 2012; 18(4): 155-161

Corresponding Author: Arzu Çoban, Türkiye


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