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Turkish Journal of Neurology Indexed By
  Cerebral Malaria: Case Report [Turk J Neurol]
Turk J Neurol. 2010; 16(3): 149-153

Cerebral Malaria: Case Report

Serhat Tokgöz1, Esra Eruyar1, Ayşegül Öğmegül1, İbrahim Erayman2
1Department Of Neurology, Selcuk University, Konya, Turkey
2Department Of Infection Diseases, Selcuk University, Konya, Turkey

Cerebral malaria is a rare complication caused by Plasmodium infection. Capillary blockage caused by infected erythrocytes, microglia activation and apoptosis of astrocytes as a result of cytokine leakage to the parenchyma are cited in the pathogenesis. Recently, a concept has evolved that metabolic changes in the brain in malaria infection may also be responsible for the epilepsy and encephalopathy pathogenesis. A 25-year-old male was admitted to our clinic for seizures and encephalopathy. The patient, diagnosed with cerebral malaria, recovered with antiedema, antiepileptic and antimalarial therapy. The pathophysiology and clinical and laboratory findings are discussed in light of the literature.

Keywords: Malaria, cerebral, epilepsy.


Serhat Tokgöz, Esra Eruyar, Ayşegül Öğmegül, İbrahim Erayman. Cerebral Malaria: Case Report. Turk J Neurol. 2010; 16(3): 149-153

Corresponding Author: Serhat Tokgöz, Türkiye


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