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POEMS Syndrome: Report of Three Cases with Review of the Literature [Turk J Neurol]
Turk J Neurol. 2011; 17(2): 110-118

POEMS Syndrome: Report of Three Cases with Review of the Literature

Somanath Padhi1, Tara Roshni Paul2, Rajlaxmi Sarangi3, Shantveer Uppin2, Sundaram Challa2, Putcha Deekshanti Narayan4
1Department Of Pathology, Pondicherry Institute Of Medical Sciences, Pondicherry, India
2Department Of Pathology, Nizamís Institute Of Medical Sciences,panjagutta, Hyderabad, India
3Post Graduate Department Of Biochemistry, M.k.c.g Medical College, Berhampur, Orissa, India
4Department Of Neurology, Nizamís Institute Of Medical Sciences, Panjagutta, Hyderabad, India

Polyneuropathy (P), organomegaly (O), endocrinopathy (E), monoclonal gammopathy (M), and skin changes(S) (POEMS) syndrome is a rare multisystemic disease that occurs in the setting of plasma cell dyscrasia. Several hundred cases have been reported in world literature. The exact prevalence is not known as the syndrome may be underreported. We reported three such cases (two males, one female) over a period of five years (January 2005 to December 2009). The clinicopathological, radiological, biochemical, and therapeutic outcome data of all the three cases are presented with a review of literature. Awareness about this entity and multidisciplinary approach is essential to make a diagnosis in these patients.

Keywords: POEMS syndrome, Polyneuropathy, Radiology, Therapy, Outcome.


Somanath Padhi, Tara Roshni Paul, Rajlaxmi Sarangi, Shantveer Uppin, Sundaram Challa, Putcha Deekshanti Narayan. POEMS Syndrome: Report of Three Cases with Review of the Literature. Turk J Neurol. 2011; 17(2): 110-118

Corresponding Author: Somanath Padhi, India


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