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Demographic and Clinical Characteristics of Patients With Epilepsy Applying to Neurology Outpaitent Clinic of Erzincan University Mengucek Gazi Education and Research Hospital [Turk J Neurol]
Turk J Neurol. Ahead of Print: TJN-14238

Demographic and Clinical Characteristics of Patients With Epilepsy Applying to Neurology Outpaitent Clinic of Erzincan University Mengucek Gazi Education and Research Hospital

Alevtina Ersoy, Ceyda Tanoğlu, Hasan Yaşar, Tuğçe Özdemir Gültekin
Erzincan University Mengucek Gazi Education and Research Hospital, Erzincan, Turkey

Objective: The aim of this study was to evoluate demographic and clinical findings of patients with epilepsy in the Erzincan region.
Materials and Methods: Five-hundred-forty-eight adult patients with epilepsy who attend neurology outpatient clinic between January 2016 - August 2017 were included in this study. Patients' age, sex, duration of epilepsy, risk factors, seizure frequency and type, number of drugs used, comorbid diseases, electroencephalography (EEG), and neuroimaging results were retrospective evaluated.
Results: Two-hundred-eigthy-three patients were men (%51.6), 265 were women (%48.4). Mean age was 40,64±17,9, mean illness duration was 11±11 year. Risk factors of epilepsy were found in 52.2% of the patient. Patologic findings in neuroimaging were found in 46.8% of patients and 48.2% of patients had patologic fidings in EEG. Thirteen percent of patients had more than one seizure per month. Eight point nine percent of patients had a seizure-free period for five years. Focal onset seizures were present in 54.8% of patients and generalized onset seizures were present in 44.5% of patients. Fifty-eight point nine percent of the patients received monotherapy and 40.3% of the patients received polytherapy. Epilepsy is accompanied by other diseases in 27.7% of the patients. There was no significant difference between genders in terms of epileptic onset age and duration, seizure frequency, number of medications used, psychiatric comorbidity, presence of pathologic findings in EEG and neuroimaging (p>0.05). Patients with pathologic findings on neuroimaging were significantly older than 18 years of age (p=0.004). Pathologic EEG findings were detected more frequently in the same patients (p=0.001). Patients with psychiatric symptoms had longer epilepsy duration (p=0.005), and the number of antiepileptic drugs used was higher (p=0.000).
Conclusion: Epilepsy does not show gender difference in terms of many features. In adult onset, pathologic findings are common in neuroimaging and EEG. Comorbid psychiatric disorders is associated with a longer and more resistant course of epilepsy.

Keywords: Epilepsy, epidemiology, neuroimaging, comorbidity




Corresponding Author: Alevtina Ersoy, Türkiye


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