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Polysomnographic Findings in A Late Onset Wilson’s Disease Patient [Turk J Neurol]
Turk J Neurol. 2007; 13(2): 127-130

Polysomnographic Findings in A Late Onset Wilson’s Disease Patient

Barış Metin, Melih Tütüncü, Derya Kaynak, Hakan Kaynak
Sleep Disorders Unit, Department Of Neurology, İstanbul University, İstanbul, Turkey

Scientific BACKGROUND: Wilson’s disease (WD) is an autosomal recessive
degenerative disorder of copper metabolism. As a degenerative disease affecting
many parts of CNS, WD has the potential to disrupt sleep regulatory mechanisms
and to cause sleep disturbances like other neurodegenerative diseases. Sleep in
WD has not been extensively studied before.
OBJECTIVES: A late onset WD patient who applied to our out-patient clinic for
sleep related problems has been extensively evaluated with clinical and
laboratory measures.
MATERIALS-METHODS: We performed three polysomnographic evaluations, one followed by continuous daytime recording.
RESULTS: We diagnosed various abnormalities including breathing, circadian
rhythm and movement disorders related to sleep.
CONCLUSIONS: Sleep disorders in WD might be a major contributor to morbidity
and mortality.

Keywords: Wilson’s disase, sleep, polysomnography


Barış Metin, Melih Tütüncü, Derya Kaynak, Hakan Kaynak. Polysomnographic Findings in A Late Onset Wilson’s Disease Patient. Turk J Neurol. 2007; 13(2): 127-130

Corresponding Author: Barış Metin, Türkiye


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